On November 26. 2006, Reuters' Will Boggs reported the results of a pre-clinical study modeling stroke using animals in South Korea. Dr. Rau stated that hypoxia-dependent nitrous oxide produced from ischemic brains was shown to have some protective properties during evolution of a stroke in laboratory rats. Whether or not the nitrous oxide was beneficial or harmful depended upon several environmental and quantitative factors. Infusions of sodium nitrite was shown to be more beneficial than sugar-water when administered to ischemic rats. Pre-treatments with the infusions before occuring strokes had no benefit. If more pre-clinical study confirms that sodium nitrite infusion is beneficial, then clinical studies will be considered.
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http://www.medscape.com/viewarticle/548236
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